One of the most interesting places that I visited during my recent trip to the Mexican state of Sinaloa was the Los Osuna tequila factory, which is located about an hour's drive from Mazatlan. At one time, there were over 100 tequila factories in the Mazatlan area, but apparently they were all closed by the Mexican government. Los Osuna has reopened, both as a working factory and as a tourist attraction. The 19th-century hacienda is something of a museum, with ancient machinery and artifacts such as antique tequila bottles on display. Los Osuna still processes the Blue Agave plant using traditional methods and takes pride in the purity of its final product, which has no cane sugar or other additives found in lower quality brands.
Even though its tequila is definitely the real thing, Los Osuna can't use the word "Tequila" on its bottle labels since the state of Jalisco owns copyright to the name. Consequently, Los Osuna calls its tequila "Distilado 100% Agave Azul." You can easily get to the factory from Mazatlan by rental car, but don't spend too long at the tequila sampling table before heading back to town. Another alternative is to sign up for one of the tours offered by operators in Mazatlan, and leave the driving to them.
To get to Los Osuna, drive north of Mazatlan on Highway 15 and turn right on the road to La Noria. The tequila factory is located a few miles before La Noria.